Background: | C1s proenzyme is the native form of C1s enzyme and is a subunit of the C1 complex. C1s proenzyme is an inactive zymogen until C1 is activated. C1 complex binds to and is activated by antigen-antibody complexes yielding C1r enzyme. C1r enzyme in the C1 complex activates C1s proenzyme generating C1s enzyme. |
Storage: | -70℃ or below. Avoid freeze/thaw. |
Source: | Normal human serum |
Purity: | >90 % by SDS PAGE. |
Molecular Weight: Size: | 86,000 Da (1 chain) 250 µg/vial |
Concentration: | 1.0 mg/ml |
Activity: | >80 % C1s binds 1:1 with excess C1-INH after activation |
Buffer: | 50 mM sodium phosphate, 130 mM NaCl, pH 7.2 |
Preservative: | None, 0.22 µm filtered. |
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